This site complies with the HONcode standard for trustworthy health information: verify here. Imdur, Monoket (isosorbide mononitrate) dosing, indications - Medscape About one-half of adults in the United States say they have used one or more supplements in the past 30 days. coma (loss of consciousness for a period of time). Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. It is not intended as medical advice for individual conditions or treatment. Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. Herbal supplements and heart medicines may not mix, Your blood pressure, if you also take a drug to treat high blood pressure, Beta blockers, such as atenolol (Tenormin), nadolol (Corgard) or propranolol (Inderal LA, Innopran XL), Calcium channel blockers, such as diltiazem, nifedipine (Procardia) and verapamil (Calan SR, Verelan), Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil), Statins, such as atorvastatin (Lipitor), lovastatin (Altoprev) and rosuvastatin (Crestor), Anti-rejection medicine, also called immunosuppressant medicine, such as cyclosporine (Gengraf, Neoral, Sandimmune). We study 23,548 Isosorbide mononitrate users. HHS Vulnerability Disclosure, Help Follow directions about how much medicine to take. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. Properly discard this product when it is expired or no longer needed. Tachjian A, et al. Bethesda, MD 20894, Web Policies Advertising revenue supports our not-for-profit mission. Isosorbide mononitrate (Monoket) can cause some serious health issues. If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). All rights reserved. Isosorbide mononitrate dose and side-effects info | Patient Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Let your provider know if you are using any medications for erectile dysfunction before you start taking isosorbide mononitrate (Monoket). URL of this page: https://medlineplus.gov/druginfo/meds/a682348.html. If you are a Mayo Clinic patient, this could Minimally clinically significant. Classes: Nitrates, Angina Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths tablet 10mg 20mg. I strongly feel that there is coronary ischemia. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. This medication belongs to a class of drugs known as. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. Is not subject to the Controlled Substances Act. You need to take it every day in order for it to work. Results: Natural Medicines. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. MeSH Don't drink alcohol while taking isosorbide mononitrate (Monoket). CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Generic alternatives may be available. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: It's not suggested to take St. John's wort if you take blood thinners. Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). Good at preventing chest pain caused by heart disease, Available as a generic version, making it less expensive, Long-acting version only needs to be taken once daily, Short-acting tablets have to be taken on a very specific schedule for the medication to work best. These side effects may go away during treatment as your body adjusts to the medicine. Alcohol will increase the risk of you experiencing side-effects such as feeling dizzy and light-headed. Can isosorbide mononitrate cause problems? If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Treatment and prognosis of heart failure with preserved ejection . Learn to reduce stress through mindful living. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. In Canada - Call your doctor for medical advice about side effects. It is in the nitrate class of drugs. Unless your doctor tells you otherwise, continue your normal diet. This makes it easier for your heart to pump, relieving heart-related chest pain. Licorice. Herbal medications in cardiovascular medicine. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. Mayo Clinic. and transmitted securely. you should know that isosorbide may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, or at any time, especially if you have been drinking alcoholic beverages. Generic alternatives may be available. 19 are major, 174 are moderate, and 2 are minor. Drug interactions may change how your medications work or increase your risk for serious side effects. flushing - try to cut down on coffee, tea and alcohol because they can make flushing worse. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Isosorbide Mononitrate side effects by likelihood and severity. This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). Last Revised - 09/15/2019. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Accessed Sept. 7, 2022. The .gov means its official. Moderately clinically significant. Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets; Merus Labs Luxco S.a.R.L, The electronic Medicines Compendium. By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. Isosorbide-2,5-dinitrate and isosorbide-5-mononitrate, the low-potent organic nitrates, are directly metabolized in the endoplasmic reticulum of the vascular smooth muscle cells via cytochrome P450 enzymes, resulting in direct production of nitric oxide (Mnzel et al., 2005).In contrast, the highly potent organic nitrates such as glyceryl trinitrate (GTN) and pentaerythritile tetranitrate . Many common herbal supplements interact with common heart medicines. Do not take more or less of it or take it more often than prescribed by your doctor. You may report side effects to Health Canada at 1-866-234-2345. See also: nitroglycerin side effects in more detail. It is components of vit. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Isosorbide mononitrate 30% immediate-release 70% sustained-release formulation: a review. It might help to take isosorbide mononitrate and dinitrate after meals. Does Isosorbide Mononitrate interact with other medications? Do not stop taking isosorbide without talking to your doctor. other information we have about you. Natural Medicines. Isosorbide mononitrate Alternatives Compared - Drugs.com Pregnancy:Data on the use of isosorbide mononitrate during pregnancy are insufficient to be able to assess the possible harmful effect. Once- versus twice-daily administration of controlled-release isosorbide-5-mononitrate 60 mg in the treatment of stable angina pectoris. If you have any questions about this medicine ask your pharmacist. Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. My cardiologist recommended I get on metropolol. AHFS Patient Medication Information. It is important that you follow the instructions your doctor gives to you about when to take your doses. 55 ratings on Drugs.com. Isosorbide mononitrate helps to prevent angina chest pain from developing. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. Accessed Sept. 7, 2022. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. What conditions does Isosorbide Mononitrate treat? Imdur vs. Isordil - RxList Contact your doctor immediately if you experience any of the following: The following side effects may get better over time as your body gets used to the medication. This is because the tablets/capsules are specially made to release the medicine they contain in a controlled way. Let your doctor know immediately if you continue to experience these symptoms or if they worsen over time. Consult your pharmacist or local waste disposal company. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. Isosorbide mononitrate belongs to the group of medicines called nitrates. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. A very serious allergic reaction to this drug is rare. Isosorbide Mononitrate (Oral Route) - Mayo Clinic Things to remember when you fill your prescription. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). You will find a full list in the manufacturer's information leaflet supplied with your medicine. Herbal supplements can strongly affect the body. Thirty percent of the patients never experienced headache from the given dosages. It does not work fast enough to relieve the pain of an angina attack that has already started. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. PMC If we combine this information with your protected Isosorbide dinitrate dose 30-120 mg daily in divided doses. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. And as many as 25% of people also take medicines ordered for them by their health care providers, also called prescription medicines. Try to keep your regular appointments with your doctor. Prescribed for Angina, Anal Fissure and Nitrate-induced headache in patients with stable angina pectoris What should I know about storage and disposal of this medication? There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. Isosorbide may not work as well after you have taken it for some time or if you have taken many doses. Isosorbide mononitrate (Monoket) is good for a specific type of chest pain (called angina), but it can cause headaches or dizziness after you take it. If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. Avoid combinations; the risk of the interaction outweighs the benefit. Dated October 2016. 46 ratings on Drugs.com. It will not treat an angina attack that has already begun. This is called a medicine interaction. isosorbide mononitrate, along with It works by relaxing the blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or . McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. Copyright 2023 IBM Watson Health. Elantan, Imdur, Isotard, Monomax, Tardisc, Xismox. What are the side effects of Isosorbide Mononitrate ? Almost 70% of older adults use them. Isosorbide mononitrate is very similar to isosorbide dinitrate. Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. Ask your pharmacist any questions you have about refilling your prescription. the unsubscribe link in the e-mail. The herb licorice may lower warfarin levels and can add to digoxin's effects. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. Now, youll enjoy a streamlined experience created specifically for healthcare providers. For even more savings, use a GoodRx coupon and pay just a fraction of the retail price. Mayo Clinic does not endorse companies or products. The narrowing makes it more difficult for blood to flow to your heart muscle. It is usually caused by narrowing of your coronary arteries due to a build-up of a fatty substance called atheroma. These products are provided 'AS IS' and 'as available' for use, without warranties of any kind, either express or implied. The tablet usually is taken two or three times daily. Swallow the tablet/capsule whole - do not chew or crush it before you swallow. Cleophas TJ, Niemeyer MG, van Der Wall EE. To view a report comparing 3 (or more) medications, please sign in or create an account. Take isosorbide exactly as directed. Alcohol, including beer, wine, and spirits, does raise your blood pressure if its consumed in excess. Take the missed dose as soon as you remember it. Isosorbide mononitrate should not be used in patients with severe anaemia, severe hypotension, closed angle glaucoma or severe hypovolaemia.Isosorbide mononitrate may give rise to postural hypotension and syncope in some patients. Isosorbide mononitrate is a nitrate-class drug used for the prophylactic treatment of angina pectoris; that is, it is taken in order to prevent or at least reduce the occurrence of angina. Use of herbal products and potential interactions in patients with cardiovascular diseases. View all Keep all medicines out of the reach and sight of children. Unable to load your collection due to an error, Unable to load your delegates due to an error. ask your doctor about the safe use of alcoholic beverages while you are taking isosorbide. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or to 30 mg 5-ISMN od for one week followed by 60 mg 5-ISMN od for one week. Below is the list of medicines, which contains Isosorbide Mononitrate as ingredient. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Alternative cancer treatments: 11 options to consider. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Your doctor may recommend treating headaches with an over-the-counter pain reliever (such as acetaminophen, aspirin). See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. We asked 34 people what they think about isosorbide mononitrate (Monoket): Get Isosorbide mononitrate (Monoket) for as low as $29.86, 180 tablets of isosorbide mononitrate 10mg. The use of the Truven Health products is at your sole risk. Background: Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. If you have recently had a head injury or a heart attack. Careers. If you are having an operation or dental treatment, please remember to tell the person carrying out the treatment which medicines you are taking. Conclusions: It is used to treat and prevent a wide range of different conditions. Natural Medicines. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Do not drink alcohol while taking View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Cardizem Alternatives Compared - Drugs.com Using this medicine with any of the following medicines is not recommended. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. However, you should not flush this medication down the toilet. This site complies with the HONcode standard for trustworthy health information: verify here. A single copy of these materials may be reprinted for noncommercial personal use only. 2023 eHealthMe.com. privacy practices. Your doctor will schedule your doses so that there is a period of time every day when you are not exposed to isosorbide. amlodipine, lisinopril, aspirin, metoprolol, furosemide, carvedilol, propranolol, spironolactone, atenolol, diltiazem. This form of skin cancer is mostly caused by PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care, MBBS, Master in Healthcare Administration, Diploma in Occupational Health, What are the uses of Isosorbide Mononitrate. Isosorbide-5-mononitrate ISMN usually begins acting within 30 minutes and its effects last six to eight hours. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Your doctor will prescribe you a short-acting nitrate for you to take if this happens. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. There are a number of medications that your doctor can prescribe in place of isosorbide mononitrate (Monoket). Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. Stopping isosorbide mononitrate (Monoket) suddenly can cause you to have a worsening of your chest pain. For details see our conditions. Accessed Sept. 7, 2022. Elsevier; 2021. https://www.clinicalkey.com. View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. Mehta D. Herbal & dietary supplements. Natural Medicines. 67% of reviewers reported a positive effect, while 13% reported a negative effect. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. American Society of Health-System Pharmacists, Inc. Disclaimer, U.S. Department of Health and Human Services. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. This product is available in the following dosage forms: There is a problem with 1998 Oct;61(10):577-83. Yet significantly fewer patients had headache on low dosage than on high dosage (45 vs 57, P < 0.02). The effects of this exposure on a nursing infant are unknown. Natural Medicines. ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. While both isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat) are both nitrate vasodilators, they are not the same medication. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.